Dealer
Can Marijuana Reduce Social Pain?
Timothy Deckman et al.
Social Psychological and Personality Science, forthcoming
Abstract:
Social and physical pain share common overlap at linguistic, behavioral, and neural levels. Prior research has shown that acetaminophen - an analgesic medication that acts indirectly through cannabinoid 1 receptors - reduces the social pain associated with exclusion. Yet, no work has examined if other drugs that act on similar receptors, such as marijuana, also reduce social pain. Across four methodologically diverse samples, marijuana use consistently buffered people from the negative consequences associated with loneliness and social exclusion. These effects were replicated using cross-sectional, longitudinal, and experimental designs. These findings offer novel evidence supporting common overlap between social and physical pain processes.
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Alcohol Reverses Religion's Prosocial Influence on Aggression
Aaron Duke & Peter Giancola
Journal for the Scientific Study of Religion, June 2013, Pages 279-292
Abstract:
The relationship between religion and violence is controversial. Discrepant findings exist between survey studies and the limited number of experimental investigations of religiosity's influence on aggressive behavior. We have attempted to resolve this discrepancy by addressing previous limitations in the literature and assessing a heretofore-untested moderator of religiosity and aggression: alcohol intoxication. This investigation included a community sample of 251 men and 269 women randomly assigned to either an acute alcohol intoxication condition or a placebo condition. Participants completed a series of questions drawn from standardized instruments of religiosity and spirituality prior to competing on an aggression laboratory paradigm in which electric shocks were received from, and administered to, a fictitious opponent under the guise of a competitive reaction-time task. Hierarchical regression analyses revealed a significant beverage-by-religiosity interaction. Religiosity predicted lower levels of aggression for participants in the placebo group and higher levels of aggression for intoxicated participants. Results indicated that high religiosity coupled with alcohol intoxication may be a risk factor for aggression. This novel finding may help to clarify previous discrepancies in studies of religiosity and aggression.
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Drinking drivers and drug use on weekend nights in the United States
Robert Voas et al.
Drug and Alcohol Dependence, 1 June 2013, Pages 215-221
Background: Studies of drinking drivers in alcohol-related crashes have shown that high breath-alcohol concentrations (BrACs) are associated with illegal drug use. Until the 2007 National Roadside Survey (NRS), the prevalence of drugs among drinking drivers on U.S. roads was unknown. Using NRS data, we explore how many drivers with positive BrACs may also be using drugs and their significance to current drinking-driving enforcement procedures.
Methods: Based on a stratified, random sample covering the 48 U.S. contiguous states, we conducted surveys on weekend nights from July-November 2007. Of the 8384 eligible motorists contacted, 85.4% provided a breath sample; 70.0%, an oral fluid sample; and 39.1%, a blood sample. We conducted regression analyses on 5912 participants with a breath test and an oral fluid or blood test. The dependent variables of interest were illegal drugs (cocaine, cannabinoids, street drugs, street amphetamines, and opiates) and medicinal drugs (prescription and over-the-counter).
Results: 10.5% of nondrinking drivers were using illegal drugs, and 26 to 33% of drivers with illegal BrACs (≥0.08 g/dL) were using illegal drugs. Medicinal drug use was more common among nondrinking drivers (4.0%) than among drivers with illegal BrACs (2.4%).
Conclusions: The significant relationship between an illegal BrAC and the prevalence of an illegal drug suggests as many as 350,000 illegal drug-using drivers are arrested each year for DWI by U.S. alcohol-impaired driving enforcement. These drug-using drivers need to be identified and appropriate sanctions/treatment programs implemented for them in efforts to extend per se laws to unapprehended drug users.
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Douglas Anglin et al.
American Journal of Public Health, June 2013, Pages 1096-1102
Objectives: We determined the costs and savings attributable to the California Substance Abuse and Crime Prevention Act (SACPA), which mandated probation or continued parole with substance abuse treatment in lieu of incarceration for adult offenders convicted of nonviolent drug offenses and probation and parole violators.
Methods: We used individually linked, population-level administrative data to define intervention and control cohorts of offenders meeting SACPA eligibility criteria. Using multivariate difference-in-differences analysis, we estimated the effect of SACPA implementation on the total and domain-specific costs to state and county governments, controlling for fixed individual and county characteristics and changes in crime at the county level.
Results: The additional costs of treatment were more than offset by savings in other domains, primarily in the costs of incarceration. We estimated the statewide policy effect as an adjusted savings of $2317 (95% confidence interval = $1905, $2730) per offender over a 30-month postconviction period. SACPA implementation resulted in greater incremental cost savings for Blacks and Hispanics, who had markedly higher rates of conviction and incarceration.
Conclusions: The monetary benefits to government exceeded the additional costs of SACPA implementation and provision of treatment.
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Racial/Ethnic and Nativity Patterns of U.S. Adolescent and Young Adult Smoking
Becky Wade, Joseph Lariscy & Robert Hummer
Population Research and Policy Review, June 2013, Pages 353-371
Abstract:
We document racial/ethnic and nativity differences in U.S. smoking patterns among adolescents and young adults using the 2006 Tobacco Use Supplement to the Current Population Survey (n = 44,202). Stratifying the sample by nativity status within five racial/ethnic groups (Asian American, Mexican-American, other Hispanic, non-Hispanic black, and non-Hispanic white), and further by sex and age, we compare self-reports of lifetime smoking across groups. U.S.-born non-Hispanic whites, particularly men, report smoking more than individuals in other racial/ethnic/nativity groups. Some groups of young women (e.g., foreign-born and U.S.-born Asian Americans, foreign-born and U.S.-born Mexican-Americans, and foreign-born blacks) report extremely low levels of smoking. Foreign-born females in all of the 25-34 year old racial/ethnic groups exhibit greater proportions of never smoking than their U.S.-born counterparts. Heavy/moderate and light/intermittent smoking is generally higher in the older age group among U.S.-born males and females, whereas smoking among the foreign-born of both sexes is low at younger ages and remains low at older ages. Taken together, these findings highlight the importance of considering both race/ethnicity and nativity in assessments of smoking patterns and in strategies to reduce overall U.S. smoking prevalence and smoking-attributable health disparities.
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Curbing coca cultivation in Colombia - A framed field experiment
Marcela Ibanez & Peter Martinsson
Journal of Public Economics, forthcoming
Abstract:
This paper investigates the efficiency of carrot and stick policies to reduce investment in coca cultivation in rural Colombia. To measure behavioral responses to anti-drug policies, we conducted a framed field experiment with farmers living in one of the most important coca growing areas. Our experimental design allows identifying heterogeneous producer types and measuring their behavioral response to carrots and sticks. We provide an example on how knowledge on distribution types can be used to design an optimal anti-drug policy. We find that about one third of the farmers have moral costs that are high enough to deter them from investing in coca and hence, would require no external incentives. Yet destroying coca completely is prohibitively costly for two fifths of the participants who would require an extremely high compensation or risk of eradication.
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Toward primary prevention of extra-medical OxyContin® use among young people
David DeAndrea, John Troost & James Anthony
Preventive Medicine, forthcoming
Objective: The prevention research context includes current epidemic levels of hazards associated with extra-medical use of OxyContin® (to get high or otherwise outside prescribed boundaries) among teenagers and young adults, and a recent OxyContin® re-formulation with an intent to reduce these hazards, plus hope for possibly beneficial primary prevention impact. The aim is to create a benchmark of risk estimates for the years just prior to OxyContin® re-formulation in anticipation of potential public health benefit in future years, with a focus on teens and the youngest adults in the United States, and to compare two methods for estimating peak risk.
Method: The data are from nationally representative probability sample surveys of 12-21 year olds, yielding estimates for incidence of extra-medical OxyContin® use. Samples are of the non-institutionalized United States population, recruited and assessed in National Surveys on Drug Use and Health (NSDUH), each year from 2004 through 2008. In aggregate, the sample includes 135,552 young people who had not used OxyContin® extra-medically prior to their year of survey assessment.
Results: The main outcome was the estimated population-level age-specific incidence of extra-medical OxyContin® use, 2004-2008. We found that during the 2004-2008 interval the estimated risk accelerated from age 12 years, reached a peak value in mid-adolescence at roughly five newly incident users per 1000 persons per year (95% confidence intervals, 0.3%, 0.7%), and then declined. A meta-analysis approach to year-by-year data differentiated age patterns more clearly than a pooled estimation approach.
Conclusion: Studying young people in the United States, we have discovered that the risk of starting to use OxyContin® extra-medically rises to a peak by mid-adolescence and then declines. From a methods standpoint, the meta-analysis serves well in this context; there is no advantage to pooling survey data across years. We also discovered that during any given year a pediatrician might rarely see even one patient who has just started to use OxyContin® to get high or for other extra-medical purposes. Implications for screening are discussed.
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Drinking to Dampen Affect Variability: Findings From a College Student Sample
Nisha Gottfredson & Andrea Hussong
Journal of Studies on Alcohol and Drugs, July 2013, Pages 576-583
Objective: We hypothesized that individuals who are unable to effectively regulate emotional reactivity, which we operationalized as variability in self-reported affect throughout the day, would use alcohol more frequently and would report higher levels of drinking to cope. Further, we hypothesized that affect variation would be a stronger predictor of alcohol use or drinking to cope than level of negative affect.
Method: A total of 86 college-age students (53% female, 77% White) participated in an intensive longitudinal study for 28 days. Participants reported positive and negative affect thrice daily and reported alcohol use once daily. Participant coping motives were assessed at study initiation.
Results: Affect variability predicted increased drinking frequency and higher levels of self-reported drinking to cope. Mean level of negative affect was not related to an increased probability of drinking, nor was it related to self-reported drinking to cope. Both individual differences in affect variation and intra-individual daily fluctuations in affect were associated with an increased likelihood of drinking.
Conclusions: Our results imply that individuals with higher-than-average levels of affect variation are at risk for high levels of alcohol involvement and that people are more likely to drink on days characterized by higher-than-normal levels of fluctuation in affect. Future studies on self-medication should consider negative affect variability in addition to - or instead of - level of negative affect.
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Illicit use of prescription stimulants in a college student sample: A theory-guided analysis
Niloofar Bavarian et al.
Drug and Alcohol Dependence, forthcoming
Background: The illicit use of prescription stimulants (IUPS) has emerged as a high-risk behavior of the 21st century college student. As the study of IUPS is relatively new, we aimed to understand (1) characteristics of IUPS (i.e., initiation, administration routes, drug sources, motives, experiences), and (2) theory-guided intrapersonal, interpersonal, and environmental correlates associated with use.
Methods: Using one-stage cluster sampling, 520 students (96.3% response rate) at one Pacific Northwest University completed a paper-based, in-classroom survey on IUPS behaviors and expected correlates. Aim 1 was addressed using descriptive statistics and aim 2 was addressed via three nested logistic regression analyses guided by the Theory of Triadic Influence.
Results: The prevalence of ever engaging in IUPS during college was 25.6%. The majority (>50.0%) of users reported initiation during college, oral use, friends as the drug source, academic motives, and experiencing desired outcomes. Intrapersonal correlates associated with use included identifying as White, lower grade point average, diagnoses of attention deficit disorder, and lower avoidance self-efficacy. Interpersonal correlates of use included off-campus residence, varsity sports participation, IUPS perceptions by socializing agents, and greater behavioral norms. Exposure to prescription drug print media, greater prescription stimulant knowledge, and positive attitudes towards prescription stimulants were environmental correlates associated with use. In all models, IUPS intentions were strongly associated with use.
Conclusions: IUPS was prevalent on the campus under investigation and factors from the intrapersonal, interpersonal and environmental domains were associated with the behavior. Implications for prevention and future research are discussed.
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Lynn Disney, Robin LaVallee & Hsiao-ye Yi
American Journal of Public Health, June 2013, Pages 1090-1095
Objectives: We assessed the effect of internal possession (IP) laws, which allow law enforcement to charge underage drinkers with alcohol possession if they have ingested alcohol, on underage drinking behaviors.
Methods: We examined Youth Risk Behavior Survey (YRBS) data from 12 states with IP laws and with YRBS data before and after each law's implementation. We used logistic regression models with fixed effects for state to assess the effects of IP laws on drinking and binge drinking among high school students.
Results: Implementation of IP laws is associated with reductions in the odds of past-month drinking. This reduction was bigger among male than among female adolescents (27% vs 15%) and only significant among younger students aged 14 and 15 years (15% and 11%, respectively). Male adolescents also reported a significant reduction (24%) in the odds of past-month binge drinking under IP laws.
Conclusions: These findings suggest that IP laws are effective in reducing underage drinking, particularly among younger adolescents.
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Pan Chen & Kristen Jacobson
Journal of Adolescent Health, forthcoming
Purpose: The current study compared longitudinal relationships between college education and patterns of heavy drinking from early adolescence to adulthood for Caucasians and African-Americans.
Methods: We analyzed data from 9,988 non-Hispanic Caucasian and African-American participants from all four waves of the National Longitudinal Study of Adolescent Health. Growth curve modeling tested differences in rates of change and levels of heavy drinking from ages 13 to 31 years among non-college youth, college withdrawers, 2-year college graduates, and 4-year college graduates, and compared these differences for Caucasians and African-Americans.
Results: There were significant racial differences in relationships between college education with both changes in and levels of heavy drinking. Rates of change of heavy drinking differed significantly across the college education groups examined for Caucasians but not for African-Americans. In addition, Caucasians who graduated from 4-year colleges showed the highest levels of heavy drinking after age 20 years, although differences among the four groups diminished by the early 30s. In contrast, for African-Americans, graduates from 2- or 4-year colleges did not show higher levels of heavy drinking from ages 20 to 31 years than the non-college group. Instead, African-American participants who withdrew from college without an associate's, bachelor's, or professional degree consistently exhibited the highest levels of heavy drinking from ages 26 to 31 years.
Conclusions: The relationship between college education and increased levels of heavy drinking in young adulthood is significant for Caucasians but not African-Americans. Conversely, African-Americans are likely to be more adversely affected than are Caucasians by college withdrawal.
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Anat Maoz et al.
Neuropsychopharmacology, forthcoming
Abstract:
Cocaine addiction is a major problem for which there is no approved pharmacotherapy. We have developed a vaccine to cocaine (dAd5GNE), based on the cocaine analog GNE linked to the capsid proteins of a serotype 5 adenovirus, designed to evoke anti-cocaine antibodies which sequester cocaine in the blood, preventing access to the CNS. To assess the efficacy of dAd5GNE in a large animal model, positron emission tomography (PET) and the radiotracer [11C]PE2I were used to measure cocaine occupancy of the dopamine transporter (DAT) in nonhuman primates. Repeat administration of dAd5GNE induced high anti-cocaine titers. Before vaccination, cocaine displaced PE2I from DAT in the caudate and putamen, resulting in 62±4% cocaine occupancy. In contrast, dAd5GNE vaccinated animals showed reduced cocaine occupancy such that when anti-cocaine titers were >4 × 105, the cocaine occupancy was reduced to levels of less than 20%, significantly below the 47% threshold required to evoke the subjective "high" reported in humans.
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Peer Effects in UK Adolescent Substance Use: Never Mind the Classmates?
Duncan McVicar & Arnold Polanski
Oxford Bulletin of Economics and Statistics, forthcoming
Abstract:
This article estimates peer influences on the alcohol, tobacco and cannabis use of UK adolescents. We present evidence of large, positive and statistically significant peer effects in all three behaviours when classmates are taken as the reference group. We also find large, positive and statistically significant associations between own substance use and friends' substance use. When both reference groups are considered simultaneously, the influence of classmates either disappears or is much reduced, whereas the association between own and friends' behaviours does not change. The suggestion is that classmate behaviour is primarily relevant only inasmuch as it proxies for friends' behaviour.
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Emily Wright, Abigail Fagan & Gillian Pinchevsky
Child Abuse & Neglect, forthcoming
Abstract:
This study uses longitudinal data from the Project on Human Development in Chicago Neighborhoods (PHDCN) to examine the effects of exposure to school violence, community violence, child abuse, and parental intimate partner violence (IPV) on youths' subsequent alcohol and marijuana use. We also examine the cumulative effects of being exposed to violence across these domains. Longitudinal data were obtained from 1,655 adolescents and their primary caregivers participating in the PHDCN. The effects of adolescents' exposure to various forms of violence across different life domains were examined relative to adolescents' frequency of alcohol and marijuana use three years later. Multivariate statistical models were employed to control for a range of child, parent, and family risk factors. Exposure to violence in a one-year period increased the frequency of substance use three years later, though the specific relationships between victimization and use varied for alcohol and marijuana use. Community violence and child abuse, but not school violence or exposure to IPV, were predictive of future marijuana use. None of the independent measures of exposure to violence significantly predicted future alcohol use. Finally, the accumulation of exposure to violence across life domains was detrimental to both future alcohol and marijuana use. The findings support prior research indicating that exposure to multiple forms of violence, across multiple domains of life, negatively impacts adolescent outcomes, including substance use. The findings also suggest that the context in which exposure to violence occurs should be considered in future research, since the more domains in which youth are exposed to violence, the fewer "safe havens" they have available. Finally, a better understanding of the types of violence youth encounter and the contexts in which these experiences occur can help inform intervention efforts aimed at reducing victimization and its negative consequences.
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Adolescents' Access to Their Own Prescription Medications in the Home
Paula Lynn Ross-Durow, Sean Esteban McCabe & Carol Boyd
Journal of Adolescent Health, forthcoming
Purpose: The objective of this descriptive study was to determine adolescents' access to their own medications at home, specifically prescription pain, stimulant, antianxiety, and sedative medications.
Methods: Semistructured interviews were conducted with a cohort of 501 adolescents from two southeastern Michigan school districts. Participants were asked what medications had been prescribed to them during the previous 6 months; if they had received prescription medications, they were asked in-depth questions about them, including how medications were stored and supervised at home.
Results: The sample was comprised of adolescents in the 8th and 9th grades, and 50.9% were male. Participants were primarily white (72.9%, n = 365) or African-American (21.6%, n = 108). Slightly less than half of the adolescents (45.9%, n = 230) reported having been prescribed medications in the previous 6 months. Of this group, 14.3% (n = 33) had been prescribed pain medications, 9.6% (n = 22) stimulants, 1.7% (n = 4) antianxiety medications, and .9% (n = 2) sedatives. In total, 57 adolescents were prescribed medications in the pain, stimulant, antianxiety, or sedative categories (including controlled medications), and the majority (73.7%, n = 42) reported that they had unsupervised access to medications with abuse potential.
Conclusions: The majority of adolescents who were prescribed medications in the pain, stimulant, antianxiety, or sedative categories during the previous 6 months had unsupervised access to them at home. It is critical that clinicians educate parents and patients about the importance of proper storage and disposal of medications, particularly those with abuse potential.
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Philip Veliz, Carol Boyd & Sean McCabe
American Journal of Public Health, May 2013, Pages e28-e30
Abstract:
We assessed the nonmedical use of prescription opioids (NMUPO) among adolescents who participate in competitive sports. Using data from Monitoring the Future, we found that adolescent participants in high-injury sports had 50% higher odds of NMUPO than adolescents who did not participate in these types of sports (i.e., nonparticipants and participants in other sports). Detecting certain subpopulations of youths at risk for NMUPO should be a central concern among health care providers.
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Katinka Quintelier et al.
Human Nature, June 2013, Pages 196-217
Abstract:
Individual differences in moral views are often explained as the downstream effect of ideological commitments, such as political orientation and religiosity. Recent studies in the U.S. suggest that moral views about recreational drug use are also influenced by attitudes toward sex and that this relationship cannot be explained by ideological commitments. In this study, we investigate student samples from Belgium, The Netherlands, and Japan. We find that, in all samples, sexual attitudes are strongly related to views about recreational drug use, even after controlling for various ideological variables. We discuss our results in light of reproductive strategies as determinants of moral views.